The BioFire® FilmArray® System helps healthcare providers improve patient care and satisfaction by providing comprehensive syndromic testing, faster results, and better results. Impacts on patient care range from hastening appropriate therapy to decreasing the length of stay.
Many infections present with similar signs and symptoms. But today’s targeted infectious disease diagnostics limit testing to only the most common pathogens associated with a clinical syndrome. This leaves most infections undiagnosed and leads to additional downstream testing, patient dissatisfaction, and compromised patient care. By using a molecular syndromic approach and a broad test menu, the BioFire FilmArray System can better detect and identify the infectious agent with just one easy diagnostic test.
The BioFire FilmArray System helps healthcare providers deliver proper treatment and reduce patient hospital stays by providing fast and accurate pathogen identification. With a turnaround time of about one hour, clinicians can make vital decisions regarding hospital admission, isolation, cohorting, antiviral or antibiotic therapy, and additional diagnostic testing.
BioFire’s syndromic approach increases the probability of identifying a pathogen in patients with symptoms of an infectious disease and increases capability of detection of co-infections.
Rogers B, Shankar P, Jerris R, Kotzbauer D, Anderson E, Watson J, O’Brien L, Uwindatwa F, McNamara K, Bost JEvolution of polymerase chain reaction testing for infectious pathogens has occurred concurrent with a focus on value-based medicine. Objective – To determine if implementation of the FilmArray rapid respiratory panel (BioFire Diagnostics, Salt Lake City, Utah), with a shorter time to the test result and expanded panel, results in different outcomes for children admitted to the hospital with an acute respiratory tract illness. Patient outcomes were compared before implementation of the RRP (November 1, 2011, to January 31, 2012) versus after implementation of the RRP (November 1, 2012, to January 31, 2013). RRP decreases the duration of antibiotic use, the length of inpatient stay and the time in isolation.
The industry-leading FilmArray Respiratory Panel (RP) simultaneously detects 17 viral and 3 bacterial pathogens. The FilmArray System empowers the physician to make informed decisions quickly and with confidence. Timely and accurate test results enable physicians to take action regarding hospital admission, treatment and infection control. The FilmArray RP Panel may significantly reduce the duration of antibiotic use, the length of inpatient stay and time spent in isolation.1 Not only can this result in cost savings, it may increase patient and physician satisfaction.2,3
1. Schreckenberger PC, McAdam AJ. 2015. Point-Counterpoint: Large Multiplex PCR Panels Should Be First-Line Tests for Detection of Respiratory and Intestinal Pathogens. J Clin Microbiol 53:3110-3115.
2. Rogers BB, Shankar P, Jerris RC, Kotzbauer D, Anderson EJ, Watson JR, O’Brien LA, Uwindatwa F, McNamara K, Bost JE. 2015. Impact of a rapid respiratory panel test on patient outcomes. Arch Pathol Lab Med 139:636-641.
3. Xu M, Qin X, Astion ML, Rutledge JC, Simpson J, Jerome KR, Englund JA, Zerr DM, Migita RT, Rich S, Childs JC, Cent A, Del Beccaro MA. 2013. Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care. Am J Clin Pathol 139:118-123.
The FilmArray Blood Culture Identification (BCID) Panel simultaneously detects 27 targets making it the most comprehensive molecular diagnostic tool available for identifying sepsis-causing pathogens, and it does so significantly sooner than conventional methods. Quickly identifying bloodstream pathogens can hasten antimicrobial therapy, improve patient mortality, decrease ICU stays and reduce costs associated with life-threatening, septic cases.4,5
Utilization of the FilmArray BCID Panel in hospitals may reduce costs, support antibiotic stewardship and most importantly, improve patient care.
4. Huang AM, Newton D, Kunapuli A, Gandhi TN, Washer LL, Isip J, Collins CD, Nagel JL. 2013. Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia. Clin Infect Dis 57:1237-1245.
5. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. 2001. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29:1303-1310.
The FilmArray Gastrointestinal (GI) Panel helps healthcare providers diagnose a patient’s gastrointestinal illness, which can contribute to quality outcomes and lead to improved patient satisfaction. Rapidly identifying the causative agents of gastrointestinal illness can help reduce the length of hospital stay, eliminate the inappropriate use of antibiotics and aid in patient management decisions.
The FilmArray GI Panel combines speed, accuracy and a 22-target menu. This makes early diagnosis possible and facilitates timely and appropriate therapeutic interventions.6
6. Rand KH, Tremblay EE, Hoidal M, Fisher LB, Grau KR, Karst SM. 2015. Multiplex gastrointestinal pathogen panels: implications for infection control. Diagn Microbiol Infect Dis 82:154-157.
The FilmArray Meningitis/Encephalitis (ME) Panel helps healthcare providers diagnose infections of the central nervous system (CNS) and may improve the clinical management of patients with meningitis and encephalitis. Access to rapid results enables healthcare providers to quickly progress through the differential diagnosis to determine appropriate therapy, distinguishing between cases that require antibiotics and those in which only supportive therapy is needed. Use of the FilmArray ME Panel can lead to reduced length of stay and duration of parenteral antibiotics for children with a positive enteroviral result.7
Rapidly identifying the cause of CNS infections can allow faster decisions on appropriate therapy, improve patient care and affect patient satisfaction.
7. Lyons TW, McAdam AJ, Cohn KA, Monuteaux MC, Nigrovic LE. 2012. Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis. Journal of Hospital Medicine 7:517-520.
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