C. difficile: the most common healthcare-associated infection

Clostridioides difficile haunts care facilities, causing additional misery for patients who are already ill. In its report on antibiotic resistance threats, the CDC classified C. difficile as an urgent threat—not because it is particularly resistant to antimicrobials, but because it most often strikes those who are taking or recently took antibiotics.

For healthcare facilities and their patients, C. difficile is a menace that causes a heavy burden of expense, illness, and even death.1 Despite the urgency, various factors make it difficult to diagnose C. difficile and determine which cases are clinically significant.