The BioFire® FilmArray®
Pneumonia Panel

Syndromic infectious disease testing for Pneumonia.

Pneumonia patients are frequently over-treated with antibiotics because it is difficult to quickly identify the pathogen responsible for their symptoms. The BioFire Pneumonia Panel delivers fast, accurate pathogen identification in about an hour, which may allow physicians to put patients on appropriate therapy quicker.1,2

 

33 TARGETS IN ONE TEST

The BioFire Pneumonia Panel identifies 33 clinically relevant targets from sputum (including endotracheal aspirate) and bronchoalveolar lavage (including mini-BAL) samples. For 15 of the bacteria, the BioFire Pneumonia Panel provides semi-quantitative results, which may help determine whether an organism is a colonizer or a pathogen.

 

Request these new BioFire Pneumonia Panel kits today:

 

THE BIOFIRE
PNEUMONIA PANEL MENU


SAMPLE TYPE:
BAL: (including mini-BAL)

Sputum: (including endotracheal aspirate)

PERFORMANCE:
BAL: 96.2% Sensitivity and 98.3% Specificity1
Sputum: 96.3% Sensitivity and 97.2% Specificity1

BACTERIA:
Semi-Quantitative Bacteria

● Acinetobacter calcoaceticus-baumannii
complex
● Enterobacter cloacae complex
● Escherichia coli
● Haemophilus influenzae
● Klebsiella aerogenes
● Klebsiella oxytoca
● Klebsiella pneumoniae group
● Moraxella catarrhalis
● Proteus spp.
● Pseudomonas aeruginosa
● Serratia marcescens
● Staphylococcus aureus
● Streptococcus agalactiae
● Streptococcus pneumoniae
● Streptococcus pyogenes

ATYPICAL BACTERIA:
Qualitative Bacteria

● Chlamydia pneumoniae
● Legionella pneumophila
● Mycoplasma pneumoniae

 
 
 
 
 

VIRUSES:

● Adenovirus
● Coronavirus
● Human Metapneumovirus
● Human Rhinovirus/Enterovirus
● Influenza A
● Influenza B
● Parainfluenza Virus
● Respiratory Syncytial Virus

ANTIMICROBIAL RESISTANCE GENES:

Methicillin resistance:
mecA/C and MREJ

Carbapenemases:
● KPC
● NDM
● Oxa-48-like
● VIM
● IMP

ESBL:
● CTX-M

Semi-quantitative Results for 15 Common Colonizers

The BioFire Pneumonia Panel reports levels of organism concentration in genome copies/mL. Values are calculated based on an internal Quantified Standard Material (QSM) that is present in the pouch at a known concentration. The difference between real-time amplification of the QSM and the amplification of a target is used to extrapolate a copies/mL concentration for the target. Values calculated below 10^3.5 copies/mL are reported as “not detected.”

The BioFire Pneumonia Panel is More Sensitive Than Culture

The BioFire Pneumonia Panel detects more pathogens than culture. It is difficult to grow organisms in culture if they are fastidious or if a patient is on antibiotics when a sample is collected. The BioFire Pneumonia Panel identifies nucleic acid even when the organism will not grow in culture. In the clinical study for the BioFire Pneumonia Panel, the panel identified a bacteria in an additional 22% of BAL and 34% of sputum specimens.1

Other Available
BioFire® FilmArray® Panels

References:

  1. Data on File at BioFire Diagnostics.
  2. Buchan B.W. et al. Clinical Evaluation and Potential Impact of a Semi-Quantitative Multiplex Molecular Assay for the Identification of Pathogenic Bacteria and Viruses in Lower Respiratory specimens. American Thoracic Society Conference, May 20th 2018, San Diego CA.